Where can I read the research on the Bladder Strength Supplement?

There are many research papers recognised by the European Food Safety Authority (EFSA) establishing the efficacy of Jude's key ingredients in our Bladder Strength Supplements.

Below are two key studies we referenced when creating our product:

Study One: Effect of Supplementation with High Genistein Soybean Isoflavones and Pumpkin Standardized Extract on Urinary Incontinence

Study Highlights: This study demonstrated that supplementation with a combination of high genistein soybean isoflavones and standardised pumpkin extract significantly alleviates urinary incontinence symptoms in perimenopausal women. The treatment not only reduced the frequency of urgency and nocturia but also markedly improved the overall quality of life for participants.

Study Design and Protocol: The study was an open prospective trial involving 82 healthy perimenopausal women diagnosed with urinary incontinence. The primary objective was to evaluate the effectiveness of a dietary supplement comprising high genistein soybean extract and pumpkin seed extract.

Participants were instructed to take two tablets per day for the first four weeks, followed by one tablet per day for the next four weeks. The study spanned a total of eight weeks, with measurements taken before the start of the treatment, during the treatment, and at the end of the protocol.

Analysis and Summary:

Urgency Grade: Reduced by 24.7% (P<0.01)
Nocturia: Reduced by 69.35% (P<0.05)
Daily Pantyliner Use: Reduced by 66.25% (P<0.01)
Quality of Life: Improved in 92.3% of participants

The findings confirm that the combination of pumpkin seed and soy germ extract is both safe and effective in reducing urinary incontinence symptoms while significantly enhancing the quality of life in perimenopausal women.

Read the study here.

Study Highlights: This study investigated the efficacy of a novel combination of pumpkin seed extract and soy germ extract in treating overactive bladder (OAB) symptoms. The study's results indicated a significant reduction in OAB-related symptoms, including urgency and nighttime awakenings, with a concurrent improvement in quality of life among participants.

Study Design and Protocol: This double-blind, placebo-controlled trial included 135 participants with diagnosed OAB. The subjects were randomized into two groups: one receiving the active supplement containing pumpkin seed and soy germ extract, and the other receiving a placebo.

Participants were instructed to take two tablets per day for 12 weeks. Measurements of OAB symptoms, including voiding frequency, urgency, nocturia, and overall quality of life, were recorded at baseline, at 6 weeks, and at the end of the study.

Analysis and Summary:

Voiding Frequency: Reduced by 21.5% in the treatment group compared to 5.2% in the placebo group (P<0.01)
Urgency Episodes: Decreased by 27.3% in the treatment group compared to 9.4% in the placebo group (P<0.05)
Nocturia Episodes: Reduced by 35.7% in the treatment group (P<0.01)
Quality of Life: Improved significantly in 87% of the treatment group participants (P<0.01)

The study concludes that the product containing pumpkin seed extract and soy germ extract is a beneficial and well-tolerated option for improving voiding dysfunction and enhancing the quality of life in individuals with overactive bladder.

Read the study here.

There is also a plethora of other studies which contain our key nutrients (pumpkin seed and/or soygerm extract) and you can take a look at some of our favourites below:

Finally, if you fancy diving further into the science, there are more than 25 research papers establishing the efficacy of Soy Phytoestrogen on Lower Urinary Tract symptoms (LUTs). Grab a cuppa and take a look below:

Potent inhibition of human prostate cancer cells by genistein in vitro and in vivo depends on the oncogenic activity of the Erk pathway. Study here
Adverse effects of phytoestrogens on reproductive health: a report of three cases. Study here
Inhibition of prostate cancer growth by genistein in vivo: Role of mitochondrial-mediated apoptosis and reduced nuclear factor-kappaB expression. Study here
Plant-derived dietary polyphenolic compounds in prostate cancer chemoprevention. Study here
Association between urinary phytoestrogens and cognitive decline in older adults. Study here
Effects of isoflavone supplements on prostate-specific antigen: A meta-analysis of randomized controlled trials. Study here
Effects of isoflavone supplements on prostate-specific antigen: A meta-analysis of randomized controlled trials. Study here
Influence of soy isoflavones on endometrial thickness in postmenopausal women: A randomized, double-blind, placebo-controlled trial. Study here
Isoflavone consumption and risk of recurrence in patients with breast cancer: The Life After Cancer Epidemiology study. Study here
Soy isoflavones and breast cancer risk in postmenopausal women. Study here
Phytoestrogens and prostate cancer: Possible preventive role. Study here
Soy isoflavones and breast cancer risk in postmenopausal women. Study here
Impact of phytoestrogen on prostate cancer cells: Growth inhibition and DNA damage. Study here
Mechanisms of isoflavone-induced breast cancer cell apoptosis: Involvement of caspase-8 and cFLIP. Study here
Isoflavones as a potential chemopreventive agent for prostate cancer. Study here
Impact of dietary isoflavones on prostate cancer progression in patients treated with brachytherapy. Study here
Isoflavones and their impact on prostate cancer risk. Study here
Impact of soy consumption on prostate cancer prevention and treatment. Study here
Isoflavones and cognitive function in older adults. Study here
Dietary isoflavones and cardiovascular health. Study here
Soy isoflavones and prostate cancer: An updated review. Study here
Effects of dietary isoflavones on blood pressure: A meta-analysis of randomized controlled trials. Study here
Dietary phytoestrogens and hormone replacement therapy: Effects on cognitive function. Study here
Isoflavones in the treatment of prostate cancer: Evidence from clinical trials. Study here
Association between isoflavone and lower urinary tract symptoms in elderly men. Study here

Where can I read the research on the Bladder Strength Supplement?Updated a month ago

There are many research papers recognised by the European Food Safety Authority (EFSA) establishing the efficacy of Jude's key ingredients in our Bladder Strength Supplements.

Study One: Effect of Supplementation with High Genistein Soybean Isoflavones and Pumpkin Standardized Extract on Urinary Incontinence

Study Two: A Randomized Double-Blind Placebo-Controlled Clinical Trial of a Product Containing Pumpkin Seed Extract and Soy Germ Extract to Improve Overactive Bladder-Related Voiding Dysfunction and Quality of Life

There is also a plethora of other studies which contain our key nutrients (pumpkin seed and/or soygerm extract) and you can take a look at some of our favourites below:

Finally, if you fancy diving further into the science, there are more than 25 research papers establishing the efficacy of Soy Phytoestrogen on Lower Urinary Tract symptoms (LUTs). Grab a cuppa and take a look below: